Wednesday, September 23, 2009

Laterality in catamential seizures

Quigg M et al. Laterality and location influence catamenial seizure expression in women with partial epilepsy.  Neurology 2009; 73: 223-227. 
Authors studied 100 women enrolled in a clinical trial of hormonal therapy for localization related epilepsy  (NIH progesterone trial study group).  Extratemporal  (10), and multifocal (14) seizures occurred randomly throught the lunar cycle.  There were 5 patients with unknown seizure origin, 25 with left temporal seizures, and 29 with right temporal seizures.  Patients with left temporal seizures peaked cyclically with onset of menses, whereas right temporal lobe seizures occurred randomly.