Goldberg et al. Cortex 1989 Reticulofrontal disconnection
update see Miller Nat Rev Neurosci 2000
DA depletion in midbrain caused frontal disconnection.
"Kevin" had retrograde without anterograde amnesia
Analogy- (partial) to schizophhrenia that also affects mesolimbic (temporal) and mesocortical (frontal) projections. EG argues schizophrenia represents a top down organizing defect ie. a type of auditory agnosia. Behav Brain Sci 1991.
Saturday, September 4, 2010
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